‘Scientists say they have discovered a new gene linked with late-onset Alzheimer’s disease.
People with a damaged copy of the gene, GAB2, may be at four times increased risk of developing dementia, Neuron journal reports.
Experts said the latest findings were some of the most significant to emerge since the discovery of the ApoE4 Alzheimer’s gene.
Late-onset Alzheimer’s affects one in 10 people over 65 and half of over 85s.
The researchers, from 15 institutions including the Institute of Neurology in London, analysed the DNA of 1,411 people and found GAB2 influenced the risk of dementia among those with APOE4.’